知识产权
目前已申请中国专利13项,已授权专利6项,PCT专利2项,发表SCI文章15篇,核心期刊文章2篇。
1、Yan Yang, Xiaomin Zhang, Xiaofen Wang, Xiaomei Zhao,Tianrui Ren, Feng Wang, Bo Yu. Enhanced delivery of artemisinin and its analogues to cancer cells by their adducts with human serum transferrin. International Journal of Pharmaceutics, 2014,467:113–122.
2、Chengjun Jiang, Hangxiang Wang, Xiaomin Zhang, Zhibin Sun, Feng Wang, Jun Cheng , Haiyang Xie, Bo Yu, Lin Zhou. Deoxycholic acid-modified chitooligosaccharide/mPEG-PDLLA mixed micelles loaded with paclitaxel for enhanced antitumor efficacy”. International Journal of Pharmaceutics. 2014,475: 60-68.
3、Yanbin Sun, Bo Yu, Guoying Wang, Yongsheng Wu, Xiaomin Zhang, Tianyou Wang, Suoqing Tang, Yuan Yuan, Robert J Lee, Lesheng Teng, Shun Xu. Enhanced Antitumor Efficacy of Vitamin E TPGS-emulsified PLGA Nanoparticles for Delivery of Paclitaxel. Colloids and Surfaces B: Biointerfaces, 2014, 123, 716-723.
4、Guoming Zhou, Xiangyu Jin, Ping Zhu, Ju Yao, Yingxin Zhang, Lesheng Teng, Robert J.Lee, Xiaomin Zhang and Wei Hong. Human Serum Albumin Nanoparticles as a Novel Delivery System for Cabazitaxel. Anticancer Research. 2016, 36: 1649-1656.
5、Jianfeng Wang, Xiaomin Zhang, Yixin Cen, Xianfu Lin, Qi Wua. Antitumor gemcitabine conjugated micelles from amphiphiliccomb-like random copolymers. Colloids and Surfaces B: Biointerfaces. 2016, 146: 707–715.
6、Complete regression of xenograft tumors using biodegradablemPEG-PLA-SN38 block copolymer micelles. Colloids and Surfaces B: Biointerfaces. 2016, 142: 417–423.
7、Jing Xie, Xiaomin Zhang, Meiyu Teng, Bo Yu, Shuang Yang, Robert J Lee and Lesheng Teng. Synthesis, characterization, and evaluation of mPEG–SN38 and mPEG–PLA–SN38 micelles for cancer therapy. International Journal of Nanomedicine. 2016, 11: 1677–1686.
8、Tao Fang, Yuehan Dong, Xiaomin Zhang, Ke Xie, Li Lin and Hangxiang Wang. Integrating a novel SN38 prodrug into the PEGylated liposomal system as a robust platform for efficient cancer therapy in solid tumors. International Journal of Pharmaceutics. 2016, 512:39-48.
9、Xiaomin Zhang, Yibo Wu, Min Zhang , Jing Mao, Yun Wu, Yingxin Zhang, Ju Yao, Chang Xu, Wenli Guo, Bo Yu. Sodium cholate-enhanced polymeric micelle system for tumor-targeting delivery of paclitaxel. International Journal of Nanomedicine, 2017, 12:8779-8799.
10、Guoying Wang, Yaying Chen, Peng Wang, Yifeng Wang, Hua Hong, Yulin Li, Jiangchao Qian, Yuan Yuan, Bo Yu, Changsheng Liu. Preferential tumor accumulation and desirable interstitial penetration of poly(lactic-co-glycolic acid) nanoparticles with dual coating of chitosan oligosaccharide and polyethylene glycol-poly(d,l-lactic acid). Acta Biomaterialia. 2016, 29, 248-260.
11、Lijiang Wang, Ju Yao, Xiaomin Zhang, Yingxin Zhang, Chang Xu, Robert J. Lee,Gary Yu, Bo Yu, Lesheng Teng. Delivery of paclitaxel using nanoparticles composed of poly(ethylene oxide)-b-poly(butylene oxide) (PEO-PBO). Colloids and Surfaces B: Biointerfaces, 2018, 161:464-470.
12、Guilin Cheng, Xiaomin Zhang, Yidan Chen, Robert J. Lee, Jiangfeng Wang, Ju Yao, Yingxin Zhang, Cheng Zhang, Kaifeng Wang, Bo Yu. Anticancer activity of polymeric nanoparticles containing linoleic acid-SN38 (LA-SN38) conjugate in a murine model of colorectal cancer. Colloids and Surfaces B: Biointerfaces, 2019, 181:822-829.
13、QiShuai, GuangkuoZhao, XiaominZhang, BoYu, Robert J.Lee, Wei-KeSu. Selection of fluorescent dye for tracking biodistribution of paclitaxel in live imaging. .Colloids and Surfaces B: Biointerfaces, 2019, 181:872-878.
14、Haifei He, Ju Yao, Yingxin Zhang, Yidan Chen, Kaifeng Wang, Robert J Lee, Bo Yu,Xiaomin Zhang*. Solid lipid nanoparticles as a drug delivery system to across the blood-brain barrier. Biochemical and Biophysical Research Communications, 2019,519 385-390.
15、Yidan Chen, Junjun Wu, Fei Yang,Bo Yu, Xiaomin Zhang,Bi Chen, Linyan Gong, Liqin Mo,Lingyu Ding,Shenglin Ma,Robert J. Lee, Kaifeng Wang. Anticancer Activity of a Liposomal Formulation of β-elemene. Nanotechnology, Submitted.
16、杨艳, 张晓敏, 汪小芬等, “青蒿琥酯-转铁蛋白复合物抑制癌细胞增殖的初步研究”, 上海师范大学学报(自然科学版), 2013, 42(6): 615-622.
17、魏炜, 张英新, 张晓敏, 蒋成君,周一峰. 紫杉烷类PEG-PDLLA纳米粒的制备及其体外评价. 浙江科技学院学报,2015, 27(1):15-21.